Lower chance result letter templates
Updated 15 May 2025
Applies to England
Template A. Lower chance result letter â� Downâs syndrome screening only
Dear (name),
Re: Your first trimester screening result
You recently had the âcombined testâ� to screen for Downâs syndrome. This has shown that your baby has a lower chance of having this condition.
For this pregnancy, you have 1 chance in (number) of having a baby with Downâs syndrome.
To understand what â�1 chance in (number)â� means, imagine a group of (number) women. One of these women will be pregnant with a baby that has the condition.
We do not offer further testing at this level of chance. A lower chance result does not mean that there is no chance at all that the baby has Downâs syndrome, just that it is unlikely.
If you have any questions about your result, you can contact me using the details below.
You can find more information about antenatal screening for this condition, including details of parent support organisations, at .
Yours faithfully,
(co-ordinator name)
Antenatal screening coordinator
Office: (phone number)
Mobile: (phone number)
Email: (email address)
Template B. Lower chance result letter â� screening for all 3 conditions
Dear (name),
Re: Your first trimester screening results
You recently had the âcombined testâ� to screen for Downâs syndrome, Edwardsâ� syndrome and Patauâs syndrome. This has shown that your baby has a lower chance of having these conditions. Your individual chances for this pregnancy are as follows:
- Downâs syndrome 1 chance in (number 1)
- Edwardsâ� syndrome and Patauâs syndrome 1 chance in (number 2)
To understand what 1 chance in (number 1) means, imagine a group of (number 1) women. One of these women will be pregnant with a baby that has Downâs syndrome.
To understand what 1 chance in (number 2) means, imagine a group of (number 2) women. One of these women will be pregnant with a baby with Edwardsâ� syndrome or Patauâs syndrome.
We do not offer further testing at this level of chance. A lower chance result does not mean that there is no chance at all that the baby has Downâs syndrome, Edwardsâ� syndrome or Patauâs syndrome, just that it is unlikely.
If you have any questions about your results, you can contact me using the details below.
You can find more information about antenatal screening for these conditions, including details of parent support organisations, at .
Yours faithfully,
(co-ordinator name)
Antenatal screening coordinator
Office: (phone number)
Mobile: (phone number)
Email: (email address)
Template C. Lower chance result letter â� Edwardsâ� syndrome and Patauâs syndrome screening only
Dear (name),
Re: Your first trimester screening result
You recently had the âcombined testâ� to screen for Edwardsâ� syndrome and Patauâs syndrome. This has shown that your baby has a lower chance of having these conditions.
For this pregnancy, you have 1 chance in (number) of having a baby with Edwardsâ� syndrome or Patauâs syndrome.
To understand what this means, imagine a group of (number) women. One of these women will be pregnant with a baby that has one of the conditions.
We do not offer further testing at this level of chance. A lower chance result does not mean that there is no chance at all that the baby has Edwardsâ� syndrome or Patauâs syndrome, just that it is unlikely.
If you have any questions about your result, you can contact me using the details below.
You can find more information about antenatal screening for these conditions, including details of parent support organisations, at .
Yours faithfully,
(co-ordinator name)
Antenatal screening coordinator
Office: (phone number)
Mobile: (phone number)
Email: (email address)
Template D. Lower chance result letter quadruple test â� Downâs syndrome screening only
Dear (name),
Re: Your second trimester screening result
You recently had the âquadruple testâ� to screen for Downâs syndrome. This has shown that your baby has a lower chance of having this condition.
For this pregnancy, you have 1 chance in (number) of having a baby with Downâs syndrome.
To understand what this means, imagine a group of (number) women. One of these women will be pregnant with a baby that has the condition.
We do not offer further testing at this level of chance. A lower chance result does not mean that there is no chance at all that the baby has Downâs syndrome, just that it is unlikely.
If you have any questions about your result, you can contact me using the details below.
You can find more information about antenatal screening for these conditions, including details of parent support organisations, at .
Yours faithfully,
(co-ordinator name)
Antenatal screening coordinator
Office: (phone number)
Mobile: (phone number)
Email: (email address)